The 4 Gauge Research Hub
Evidence-Based Sports Nutrition, Performance & Hormone Health
Explore the science behind performance, recovery, testosterone support, nitric oxide production, and the ingredients that power every 4 Gauge formula.
Every article in the Research Hub is built from peer-reviewed studies, human clinical trials, and published scientific literature.
Why We Built The Research Hub
The supplement industry is filled with bold claims, proprietary blends, and marketing hype. We built the 4 Gauge Research Hub to make the science easier to understand.
Our goal is simple: explain what the research says, how specific ingredients work inside the body, and why we chose the ingredients included in our formulas.
Whether you're researching creatine, testosterone support, nitric oxide, recovery, or athletic performance, you'll find evidence-based summaries designed to help you make informed decisions.
Featured Research
Start with our most important research summaries, then explore deeper ingredient and topic-specific articles as the Research Hub grows.
The Science Behind Premium Testosterone Support
A comprehensive review of the clinical evidence behind TestoSurge®, Ashwagandha, Shilajit, Vitamin D3, Zinc, and their role in hormone health.
Read Research → Available NowThe Science Behind 4 Gauge Pre-Workout
Explore the research behind Citrulline, Beet Root, Caffeine, L-Theanine, Rhodiola, and the formula designed to deliver smooth energy and performance.
Read Research → Available NowThe Science Behind PowerPhase
Learn how Creatine, D-Ribose, Glycine, and Magnesium support ATP production, recovery, strength, and muscle performance.
Read Research → Available Now4 Gauge & Sexual Performance
A review of the scientific literature examining nitric oxide production, vascular function, libido, stress reduction, and sexual performance.
Read Research →Browse Research By Topic
Explore the major research areas behind the 4 Gauge product line.
Performance & Pre-Workout Science
Energy, focus, endurance, nitric oxide production, and athletic performance.
Muscle Growth & Recovery
Creatine, ATP production, muscle recovery, and strength development.
Testosterone & Hormone Health
Hormone optimization, cortisol management, vitality, and male performance.
Blood Flow & Nitric Oxide
The science behind citrulline, beet root, circulation, vascular function, and pumps.
Sexual Performance & Libido
Research examining blood flow, nitric oxide, libido, stress, and sexual health.
Ingredient Research
Deep dives into the individual ingredients used throughout the 4 Gauge product line.
What You'll Find In Every Research Article
Human Clinical Trials
Priority is given to randomized controlled trials and human outcome studies whenever available.
Peer-Reviewed Research
We rely on published scientific literature from established journals and research databases.
Mechanism Explanations
Understanding why an ingredient works is just as important as understanding whether it works.
Practical Takeaways
We focus on translating scientific findings into information that can actually help real people.
How We Evaluate The Research
The strongest research isn't always the newest research. When evaluating ingredients, we consider:
Whenever possible, we prioritize human outcome data over animal or laboratory findings.
- Human clinical trials
- Meta-analyses
- Systematic reviews
- Mechanistic evidence
- Real-world dosing relevance
- Safety data
- Replication across multiple studies
Pre-Workout Reference
Understand pre-workout ingredients, compare studied doses, interpret supplement labels, and learn about common side effects.
Core references
Pre-Workout Ingredient Glossary
Plain-language definitions for 30 pre-workout ingredients and label terms, with evidence notes and sources.
Open the glossary → ReferencePre-Workout Ingredient Dosage Guide
Compare studied amounts, ingredient forms, timing, and evidence limits. Understand which protocols use single doses and which use daily supplementation.
Open the dosage guide →Practical guides
How Much Caffeine Should Be in Pre-Workout?
Explore caffeine research, individual sensitivity, timing, and how coffee, energy drinks, and pre-workout contribute to your daily total.
Read the caffeine guide → GuidePre-Workout Side Effects: Causes, What to Do, and When to Stop
Understand possible causes of tingling, flushing, jitters, stomach upset, and sleep disruption, with practical next steps and warning signs.
Read the side-effects guide →Understanding formulas
Proprietary Blends vs Fully Disclosed Formulas
Learn what supplement labels reveal, what a total blend weight cannot tell you, and why disclosed ingredient amounts matter when comparing formulas.
Read the formula guide → Label guideWhat Is a Clean Pre-Workout?
Look beyond the word “clean” to evaluate ingredient forms, disclosed amounts, sweeteners, and stimulant levels.
Read the clean pre-workout guide →Ingredient Deep Dives
In-depth, evidence-based research summaries for the key ingredients across the 4 Gauge lineup.
Citrulline & Nitric Oxide
How nitric oxide impacts blood flow, pumps, endurance, and recovery.
Read the research → IngredientCreatine Performance & Recovery
The science of ATP production, strength, recovery, and lean mass development.
Read the research → IngredientAshwagandha & Testosterone
Research examining cortisol reduction, vitality, recovery, and hormone support.
Read the research → IngredientFenugreek Research
The evidence behind TestoSurge® and testosterone support.
Read the research → IngredientShilajit Research
Fulvic acid, mitochondrial function, vitality, and hormone health.
Read the research → IngredientCaffeine + L-Theanine
Human research on caffeine and L-theanine, with studied amounts, mixed athlete findings, and clear evidence limits.
Read the research →Research Backed. Performance Focused.
Every product in the 4 Gauge lineup was built around ingredients selected for both scientific support and real-world effectiveness. Explore the research behind each formula and decide for yourself whether the evidence aligns with your goals.
Premium Testosterone Support
Evidence-based hormone support featuring TestoSurge®, Ashwagandha, and Shilajit.
View Research Shop product →4 Gauge Pre-Workout
Smooth energy, focus, endurance, and nitric oxide support without the crash.
View Research Shop product →PowerPhase Creatine Stack
Creatine, D-Ribose, Glycine, and Magnesium designed to support the complete ATP cycle.
View Research Shop the range →Who Reviews Our Research
Connor Southworth
I've spent years researching sports nutrition, performance, recovery, and supplementation—not just as a business owner, but as someone passionate about strength training and health.
The goal of the Research Hub isn't to convince anyone to buy a supplement. The goal is to make the science easier to understand.
Every article is built from published research and reviewed before publication to ensure accuracy, clarity, and practical relevance.
Learn More About Connor →Research Hub FAQ
What makes the 4 Gauge Research Hub different?
Our research articles focus on peer-reviewed evidence, human clinical trials, and transparent sourcing rather than marketing claims.
Are these articles medical advice?
No. The information presented is educational in nature and should not replace professional medical advice. Always speak with a qualified healthcare professional before making changes to your supplement, training, or health routine.
How often is the research updated?
Research pages are reviewed periodically as new studies become available.
Do you only review ingredients used in 4 Gauge products?
Many articles focus on ingredients used in our formulas, but the Research Hub also covers broader topics relevant to performance, recovery, energy, and health.
Ready To Explore The Science?
Browse our research library, explore the evidence, and learn how each ingredient contributes to performance, recovery, and hormone health.
For informational and educational purposes only. These statements have not been evaluated by the FDA. 4 Gauge products are not intended to diagnose, treat, cure, or prevent any disease.